What to consider when interpreting proteomic data

** Special collaboration from the proteomic platform** Following your sample's analysis by mass spectrometry, you will usually receive your results as a list of proteins.    During the treatment of the data, some factors inevitably influence the proteins found in the final list. Fig. 1 Overview of bottom-up proteomics. Figure modified from Angel et al. (2011)   Let's begin by briefly explaining how this protein list is generated by the bottom-up approach usually used (see Figure 1).  In this [...]