SNP Filtering with pyGeno

Looking over the contents of our growing blog (good job guys !), it occured to me that we had not yet posted an article pertaining to the fantastic (and homegrown !) bioinformatics resource that is pyGeno. It turns out I need to use pyGeno to generate data and it's also my turn to write a blog post, how convenient ! I'll focus the article on writing a SNP filter, which can be a bit surprising the first time you try [...]

By | 2016-12-12T15:22:42+00:00 December 9, 2016|Categories: Bioinformatics, Python|0 Comments

Introduction to cowplot to combine several plots in one with R

Hi everyone, Today I will introduce cowplot, an extension of ggplot2 library. Some helpful extensions and modifications to the 'ggplot2' package. In particular, this package makes it easy to combine multiple 'ggplot2' plots into one and label them with letters, e.g. A, B, C, etc., as is often required for scientific publications. As you can see, this library can be useful to easily create a figure containing multiple plots. But we will see how we can use it to create [...]

By | 2016-11-28T11:39:47+00:00 November 28, 2016|Categories: Bioinformatics, Biology, Data Analysis, Data Visualisation, R|0 Comments

Pivoting tables : from long to wide

As bioinformaticians, we often have to work with data that are not formatted the way we would need them to be. One case we might encounter is receiving data in a "long" format instead of receiving them in a more familiar "wide" format. For those of you familiar with the ggplot R package, you know this format very well. It's the format required by ggplot to produce its nice graphs. Long genes samples expression 1 BAD S01 7.525395 2 BAD [...]

By | 2016-11-14T15:33:58+00:00 November 14, 2016|Categories: Python, R|0 Comments

Implementing a “Siamese” Neural Network with Mariana 1.0

Mariana was previously introduced in this blog by Geneviève in her May post Machine learning in life science. The Mariana codebase is currently standing on github at the third release candidate before the launch of the stable 1.0 release. This new version incorporates a large refactorization effort as well as many new features (a complete list of the changes found in the 1.0 version can be found in the changelog). I am taking this opportunity to present here a small tutorial on extending the [...]

By | 2016-11-25T09:29:10+00:00 November 7, 2016|Categories: Computer science, Data Analysis, Machine learning, Python|0 Comments

Fast network transfers?

Recently, everyone and their mother started using various tools in order to optimize large data transfer to, from and between supercomputers. Historically, we have seen tools like FDT, BBCP that tried to exceed the performance obtained from other transfer methods, like scp, rsync, ftp, etc. One tool in particular is now gaining traction and is being deployed on most supercomputers: GridFTP and its front-end Globus. The Globus frontend interface. Before jumping into the bandwagon, I thought it would [...]

By | 2016-11-08T09:30:02+00:00 October 13, 2016|Categories: Computer science, Performance, Test|0 Comments